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Steroid esters half life cycle

Edit: Landmark Nutraceuticals Co.,Limited    Date: May 12, 2016
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Esters


Steroid esters are made up of the steroid molecule with a carbon chain attached to it. This carbon chain determines the half-life of the steroid, and solubility in the bloodstream. Each ester contains a different number of carbon atoms, and this is what sets them apart from one another.

Ester slows the release of the parent steroid from the site of injection, which is a great benefit in steroid medicine. Free testosterone previously would remain active in the body for a very short period of time (typically hours). This would necessitate an unpleasant daily injection schedule if one wished to maintain a continuous elevation of testosterone. 


Esters and half-life 

Acetate         2 carbon ester3 days 

Propionate        3 carbon ester2 days 

Phenylpropionate    9 carbon ester4.5 days

Caproate    6 carbon ester9 days 

Isocaproate     6 carbon ester9 days 

Enanthate         7 carbon ester10.5 days 

Cypionate     8 carbon ester12 days 

Decanoate     10 carbon ester15 days 

Undecanoate     11 carbon ester16.5 days 


However, the heavier the ester chain, the greater is its percentage of the total weight. In the case of testosterone enanthate for example, 250mg of esterified steroid (testosterone enanthate) is equal to only 180mg of free testosterone.


Oral steroids Drug Active half-life 

Anadrol: 8 to 9 hours 

Anavar: 9 hours 

Dianabol: 4.5 to 6 hours 

Winstrol: 9 hours(oral) 24hours(injectable)


Ancillaries Drug Active half-life 

Arimidex 3 days 

Clenbuterol 1.5 days 

Clomid 5 days 

Cytadren 6 hours 

T3 10 hours


Half-life and cycle 

Half-life: the time period in which levels of drug drop by 50%. For example, if a drug has a one day half-life, then after one day levels will have fallen to ½, after two days to ¼, after three days to ⅛, etc.

The concept of steroid half-lives is used as a guide for optimizing your dosing schedule and organizing your cycle appropriately in order to achieve the most effective, comfortable, and safe cycle and avoid unwanted peaks and valleys in medication effects, and the often undesirable side effects which accompany such uneven up and down levels.


Some suggestions

Testosterone Propionate half-life: 4.5 days. Optimal injection frequency: every other day (daily is even better).

Trenbolone Acetate half-life: 3 days. Optimal injection frequency: every other day (daily is even better).

Testosterone Cypionate half-life: 10 – 12 days. Optimal injection frequency: twice per week, each injection split evenly between each other (for example, Monday and Thursday).

Dianabol (Methandrostenolone) half-life: 4 – 6 hours. Optimal administration frequency: once every two to four hours.


The normal progression of blood level buildup is as follows (using Testosterone Enanthate as the example compound, for the purpose of explanation, its half-life will be regarded as 7 days):


Day 1: 500mg

Day 7: 250mg remaining from the previous injection + 500mg freshly injected = 750mg total

Day 14: 375mg remaining from the previous injection + 500mg freshly injected = 875mg total

Day 28: 437.5mg remaining from the previous injection + 500mg freshly injected = 937.5mg total

Day 35: 468.75mg remaining from the previous injection + 500mg freshly injected = 968.75mg total

Day 42: 484.38mg remaining from the previous injection + 500mg freshly injected = 984.38mg total



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LandMarkChem Team

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